DNAMedsby Antares Genomics

Heritage Month Special

One sample. Two stories from your DNA.

For a limited time, every DNAMeds pharmacogenomics test includes the MyDNARoots ancestry test at no extra cost.

Heritage Month offer · 2 for 1

Two powerful insights · One price

DNAMeds Pharmacogenomics Test

Discover how your genetics influence medication response — and receive your MyDNARoots ancestry test free.

R5,500once-off

Ancestry test included free

  • 27-gene pharmacogenomics DNA test
  • Personalised medication insights report
  • MyDNARoots ancestry test included
  • Two reports from one special offer

Offer ends 30 September · Terms and conditions apply · Secure checkout via Peach Payments

Pharmacogenomic results provide genetic information to support conversations with a qualified healthcare professional. They do not diagnose conditions or replace medical advice.

Pharmacogenetic Testing

Your DNA decides
how medicine works

We all carry tiny variations in our DNA that are unique to us. Because of them, two people taking the same medication can have very different experiences — from no relief at all, to severe pain, cramping, or hospitalization from adverse drug reactions.

Golden DNA double helix with highlighted genetic variants

The Science

One DNA test. A lifetime of safer prescriptions.

Once we identify the changes in your DNA through a PGx test, we can predict — using internationally accredited guidelines — exactly how your body will respond to a given drug, so your physician can choose the right medication and the right dose.

Are all PGx tests the same?

No, all Pharmacogenomic tests are not the same. Our test has been carefully curated to offer you the maximum clinical value by testing those genes that are clinically actionable COMPREHENSIVELY across disease areas.

Our analysis and interpretation platform ensures that you have the most clinically robust recommendations vetted by expertly trained pharmacists that help you and your Doctors understand the technical report.

Exclusive to DNAMeds

Each test includes a FREE consultation with an expertly trained Pharmacogenomics Consultant Pharmacist.

Your Metabolizer Status

Four ways your body handles a drug

Poor

The drug is broken down very slowly. Standard doses build up and may cause side effects or toxicity.

Lower dose or alternative drug

Normal

Your body processes the medication as expected. Standard dosing typically works as intended.

Standard dose

Rapid

The drug is cleared faster than average. You may need a higher dose to feel the therapeutic effect.

Increased dose may be needed

Ultra-Rapid

The medication is broken down so quickly that it may not work — or, for prodrugs, may become dangerous.

Alternative drug recommended

Free Pre-Check

Check your medications for possible interactions

List every medication and supplement you currently take. We'll flag potential drug-drug interactions and show which ones a PGx test could clarify — before you commit to one.

Educational use only — not a substitute for advice from your prescriber or pharmacist. Do not change any medication without speaking to your clinician.

Common Medications Affected

Where genetic variation matters most

Cardiovascular

Anticoagulants, Beta-Blockers, Antiplatelets, Statins

Gastroenterology

Proton-Pump Inhibitors

Infectious Disease

Antivirals, Antifungals

Neurology & Anesthesia

Anticonvulsants, Anesthetics

Pulmonology

Ivacaftor

Acute Hemolytic Anemia

Primaquine, Dapsone, Rasburicase

Psychiatry

SSRIs, Tricyclic Antidepressants

Pain & Antiemetics

NSAIDs, Opioids, 5-HT3 Antagonists

Oncology

Fluoropyrimidines, Thiopurines, Estrogen Modulators

Immunology / Transplants

Immunosuppressants

The 27-Gene Panel

Genes we analyze and why they matter

Each gene below influences how your body activates, breaks down, or reacts to specific medications.

ABCG2

Transporter affecting rosuvastatin and allopurinol exposure and response.

BCHE

Butyrylcholinesterase — prolonged apnea risk with succinylcholine and mivacurium.

CACNA1S

Malignant hyperthermia susceptibility with volatile anesthetics.

CFTR

Ivacaftor and modulator response in cystic fibrosis.

CYP2B6

Efavirenz, bupropion, methadone metabolism.

CYP2C cluster

Combined haplotype context for the CYP2C gene region.

CYP2C19

Activates clopidogrel; metabolizes PPIs, SSRIs, voriconazole.

CYP2C9

Warfarin, NSAIDs, phenytoin metabolism.

CYP2D6

Metabolizes ~25% of all prescription drugs (antidepressants, opioids, antipsychotics, tamoxifen).

CYP3A4

Largest drug-metabolizing enzyme; statins, immunosuppressants.

CYP3A5

Tacrolimus dosing in transplant patients.

CYP4F2

Vitamin K recycling — warfarin dosing.

DPYD

Fluoropyrimidine (5-FU, capecitabine) toxicity risk.

FII

Prothrombin (Factor II) — thrombosis risk relevant to anticoagulation.

FV

Factor V Leiden — thrombosis risk relevant to anticoagulation and hormonal therapy.

G6PD

Hemolytic anemia risk with primaquine, dapsone, rasburicase.

HLA-A

Carbamazepine hypersensitivity (HLA-A*31:01).

HLA-B

Severe hypersensitivity to abacavir, carbamazepine, allopurinol.

IFNL3/4

Response to pegylated interferon for hepatitis C.

MT-RNR1

Aminoglycoside-induced hearing loss.

NAT2

Isoniazid, sulfonamide metabolism.

NUDT15

Thiopurine toxicity, especially in Asian populations.

RYR1

Malignant hyperthermia with volatile anesthetics.

SLCO1B1

Statin-induced myopathy risk.

TPMT

Thiopurine (azathioprine, mercaptopurine) toxicity risk.

UGT1A1

Irinotecan, atazanavir — Gilbert syndrome.

VKORC1

Warfarin sensitivity.

Full Coverage

Every drug covered by our DNAMeds List

A 27-gene panel covering more than 260 medications across every major therapeutic area — from cardiology to oncology, psychiatry to pain management.

Addiction

3
  • lofexidine
  • buprenorphine
  • methadone

Alzheimer's Disease

1
  • aducanumab

Anesthesiology

14
  • bupivacaine
  • chloroprocaine
  • desflurane
  • enflurane
  • halothane
  • isoflurane
  • mepivacaine
  • metabutethamine
  • methoxyflurane
  • oxymetazoline & tetracaine
  • prilocaine
  • ropivacaine
  • sevoflurane
  • succinylcholine

Cardiology

30
  • acenocoumarol
  • atorvastatin
  • bisoprolol & perindopril
  • carvedilol
  • clopidogrel
  • fenofibrate
  • flecainide
  • fluindione
  • fluvastatin
  • hydralazine
  • losartan
  • lovastatin
  • mavacamten
  • metoprolol
  • nebivolol
  • nicorandil
  • nitroglycerin
  • perindopril
  • pitavastatin
  • prasugrel
  • pravastatin
  • procainamide
  • propafenone
  • propranolol
  • ranolazine
  • rosuvastatin
  • simvastatin
  • ticagrelor
  • timolol
  • warfarin

Cystic Fibrosis

1
  • ivacaftor

Dental

2
  • articaine & epinephrine
  • cevimeline

Dermatology

4
  • abrocitinib
  • deuruxolitinib
  • lidocaine & prilocaine
  • lidocaine & tetracaine

Dietary Supplement

1
  • vitamin C

Endocrinology

10
  • chlorpropamide
  • gliclazide
  • glimepiride
  • glipizide
  • glyburide
  • nateglinide
  • pioglitazone
  • saxagliptin
  • tolazamide
  • tolbutamide

Fever

1
  • paracetamol

Gastroenterology

11
  • dexlansoprazole
  • dronabinol
  • esomeprazole
  • lansoprazole
  • meclizine
  • metoclopramide
  • omeprazole
  • ondansetron
  • pantoprazole
  • rabeprazole
  • tropisetron

Gaucher's Disease

1
  • eliglustat

Gynaecology

4
  • drospirenone & ethinyl estradiol
  • elagolix
  • estrogen-containing contraceptives
  • flibanserin

Hematology

4
  • avatrombopag
  • eltrombopag
  • lusutrombopag
  • phenprocoumon

Immunology

3
  • cyclosporine
  • sirolimus
  • tacrolimus

Infectious Diseases

52
  • 4-aminosalicylic acid
  • amikacin
  • atazanavir
  • chloroquine
  • ciprofloxacin
  • dapsone
  • dasabuvir
  • dibekacin
  • dolutegravir
  • efavirenz
  • flucloxacillin
  • flucytosine
  • gentamicin
  • hydroxychloroquine
  • isoniazid
  • kanamycin
  • ketoconazole
  • mafenide
  • maraviroc
  • methylene blue
  • moxifloxacin
  • nalidixic acid
  • neomycin
  • netilmicin
  • nevirapine
  • nitrofurantoin
  • norfloxacin
  • ofloxacin
  • paromomycin
  • peginterferon alfa-2A
  • peginterferon alfa-2A + ribavirin
  • peginterferon alfa-2A + ribavirin + boceprevir
  • peginterferon alfa-2A + ribavirin + simeprevir
  • peginterferon alfa-2A + ribavirin + telaprevir
  • peginterferon alfa-2B
  • peginterferon alfa-2B + ribavirin
  • peginterferon alfa-2B + ribavirin + boceprevir
  • peginterferon alfa-2B + ribavirin + simeprevir
  • peginterferon alfa-2B + ribavirin + telaprevir
  • plazomicin
  • primaquine
  • quinine
  • raltegravir
  • ribostamycin
  • sofosbuvir
  • streptomycin
  • sulfadiazine
  • sulfamethoxazole
  • sulfamethoxazole & trimethoprim
  • tafenoquine
  • tobramycin
  • voriconazole

Neurology

19
  • alprazolam
  • amifampridine
  • amifampridine phosphate
  • belzutifan
  • brivaracetam
  • clobazam
  • clonazepam
  • deutetrabenazine
  • dextromethorphan & quinidine
  • diazepam
  • donepezil
  • fosphenytoin
  • galantamine
  • lamotrigine
  • mivacurium
  • phenytoin
  • siponimod
  • tetrabenazine
  • valbenazine

Oncology

21
  • 5-fluorouracil
  • allopurinol
  • belinostat
  • capecitabine
  • cisplatin
  • dabrafenib
  • doxorubicin
  • erdafitinib
  • erlotinib
  • flutamide
  • gefitinib
  • irinotecan
  • mercaptopurine
  • nilotinib
  • pazopanib
  • rasburicase
  • sacituzumab govitecan-hziy
  • tamoxifen
  • tegafur
  • thioguanine
  • toluidine blue

Pain

20
  • aspirin
  • carbasalate calcium
  • carisoprodol
  • celecoxib
  • codeine
  • diclofenac
  • dihydrocodeine
  • fentanyl
  • flurbiprofen
  • hydrocodone
  • ibuprofen
  • lornoxicam
  • meloxicam
  • oliceridine
  • oxycodone
  • piroxicam
  • sufentanil
  • tenoxicam
  • tolperisone
  • tramadol

Psychiatry

47
  • amitriptyline
  • amoxapine
  • amphetamine
  • aripiprazole
  • aripiprazole lauroxil
  • atomoxetine
  • brexpiprazole
  • bupropion
  • buspirone
  • citalopram
  • clomipramine
  • clozapine
  • desipramine
  • dextromethorphan
  • dextromethorphan & bupropion
  • doxepin
  • duloxetine
  • escitalopram
  • eszopiclone
  • fluoxetine
  • flupenthixol
  • fluvoxamine
  • guanfacine
  • haloperidol
  • iloperidone
  • imipramine
  • mirtazapine
  • moclobemide
  • nortriptyline
  • olanzapine
  • paroxetine
  • perphenazine
  • pimozide
  • pitolisant
  • protriptyline
  • quetiapine
  • risperidone
  • sertindole
  • sertraline
  • thioridazine
  • trazodone
  • trimipramine
  • venlafaxine
  • desvenlafaxine
  • viloxazine
  • vortioxetine
  • zuclopenthixol

Rheumatology

4
  • azathioprine
  • lesinurad
  • pegloticase
  • sulfasalazine

Toxicology

1
  • sodium nitrite

Urology

6
  • dapoxetine
  • darifenacin
  • fesoterodine
  • mirabegron
  • tamsulosin
  • tolterodine
Heritage Month · 2 for 1

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